Current Updates on the Role of Microbiome in Endometriosis: A Narrative Review

Type: Review

Published: January 31, 2023

Journal: Microorganisms

DOI: 10.3390/microorganisms11020360

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Image: Fred Hutchinson Cancer Center

Key Takeaways:

Researchers discovered that the microbiome and endometriosis development are bidirectional related, suggesting that the host’s microbiome can impact endometriosis.

Emerging evidence has highlighted the potential of crosstalk between microbiomes of different sites in several diseases, including the urogenital and gut microbiome. There is growing evidence that people with endometriosis have higher levels of bacterial colonization in their endometrial tissues and menstrual blood than those who do not.

Microbiome-based therapeutics may potentially be used in the future to restore microbiomes and alleviate chronic inflammation.

The search for microbial-derived disease biomarkers for endometriosis is still in very early stages, especially for clinical applications. Further studies are needed.

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